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Advanced filters: Author: Nataliya Uboha Clear advanced filters

Quemliclustat and chemotherapy with or without zimberelimab in metastatic pancreatic adenocarcinoma: a randomized phase 1 trial

In a phase 1b trial, patients with treatment-naive metastatic pancreatic adenocarcinoma received the CD73 inhibitor quemliclustat plus gemcitabine and nabpaclitaxel with or without the anti-PD1 antibody zimberelimab, showing encouraging clinical response rates and survival in quemliclustat-treated patients.

Zev A. Wainberg
Gulam A. Manji
Eileen M. O’Reilly
ResearchOpen Access30 Mar 2026
Nature Medicine

P: 1-11
Subclonal response heterogeneity to define cancer organoid therapeutic sensitivity

Jeremy D. Kratz
Shujah Rehman
Dustin A. Deming
ResearchOpen Access09 Apr 2025
Scientific Reports

Volume: 15, P: 1-17
NCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in previously treated metastatic gastric and gastroesophageal junction adenocarcinoma

Michael Cecchini
James M. Cleary
Jill Lacy
ResearchOpen Access22 Dec 2023
British Journal of Cancer

Volume: 130, P: 476-482

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