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Showing 1–3 of 3 results
Advanced filters: Author: Nataliya Zhukova Clear advanced filters
  • H3K27-altered diffuse midline gliomas are a highly aggressive form of paediatric brain cancer. Here, the authors present molecular profiling of 68 patients, and show the efficacy of precision-guided therapy based on this profiling.

    • Campbell J. L. McKay
    • Chelsea Mayoh
    • Dong-Anh Khuong-Quang
    ResearchOpen Access
    Nature Communications
    P: 1-11
  • In the observational ZERO Childhood Cancer Precision Medicine Program PRecISion Medicine for Children with Cancer (PRISM) trial, children with high-risk cancer were treated with molecular tumor board-recommended therapies, resulting in overall clinical response rates that translated into survival benefit after long-term follow-up.

    • Loretta M. S. Lau
    • Dong-Anh Khuong-Quang
    • David S. Ziegler
    ResearchOpen Access
    Nature Medicine
    Volume: 30, P: 1913-1922
  • Infant gliomas behave differently to their childhood or adult counterparts. Here, the authors perform a large-scale genetic analysis of these tumours, revealing genetic alterations which may offer therapeutic opportunities.

    • Ana S. Guerreiro Stucklin
    • Scott Ryall
    • Cynthia Hawkins
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13