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Showing 1–4 of 4 results
Advanced filters: Author: Nathan E. Schoppa Clear advanced filters

  • Each olfactory sensory neuron in mice is defined by which of the ∼1,000 odorant receptor genes that it expresses. Using optogenetics, a study finds that mice can perceive stimulation of only a single class of olfactory sensory neuron.

    • Nathan E Schoppa
    News & Views
    Nature Neuroscience
    Volume: 16, P: 1516-1517

  • Many sensory brain areas are characterized by a specific spatial organization, with neurons being ordered according to their similarity in receptive field properties. A surprising new study provides evidence that the organization of glomeruli in the olfactory bulb violates this anatomical principle, suggesting that olfaction might work by a different set of rules.

    • Nathan E Schoppa
    News & Views
    Nature Neuroscience
    Volume: 12, P: 103-104

  • Munc18-1 binds trans-SNARE complexes and promotes membrane fusion in vitro. Here the authors provide genetic evidence that this trans-SNARE-regulating function plays an essential role in synaptic releases in neurons, and show that this function is disrupted by a disease-causing Munc18-1 mutation.

    • Chong Shen
    • Shailendra S. Rathore
    • Jingshi Shen
    Research
    Nature Communications
    Volume: 6, P: 1-10