In the POST trial, mechanical ischaemic postconditioning did not have a significant cardioprotective effect in patients with ST-segment elevation myocardial infarction. However, the sample size, the principal end point (ST-segment regression), and the postconditioning protocol used are important limitations in this trial. Whether mechanical postconditioning has cardioprotective clinical benefits remains unanswered.
- Michel Ovize
- Nathan Mewton
