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Showing 1–3 of 3 results
Advanced filters: Author: Nathaniel Skillin Clear advanced filters
  • Activation of interleukin-17 (IL-17) receptor signaling within intestinal epithelial cells (IECs) promotes colorectal cancer development. Here, the authors show that miR-146a limits inflammation-induced colorectal carcinogenesis by inhibiting both IL-17 induction from myeloid cells and inhibiting IL-17R signaling within IECs.

    • Lucien P. Garo
    • Amrendra K. Ajay
    • Gopal Murugaiyan
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16
  • Many immune functions have been reported for γδ T cells, including the regulation of antibody responses. Here the authors show that CXCR5+ γδ T cells release Wnt ligands to initiate the T follicular helper cell differentiation program and promote antibody production.

    • Rafael M. Rezende
    • Amanda J. Lanser
    • Howard L. Weiner
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13