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Showing 1–9 of 9 results
Advanced filters: Author: Neda Bernasconi Clear advanced filters

  • Xie and colleagues show that MRI-based brain function maps can identify patient-specific abnormalities in temporal lobe epilepsy, track how they spread along brain networks, and help diagnose, lateralize seizure focus, and predict surgical outcomes.

    • Ke Xie
    • Ella Sahlas
    • Boris C. Bernhardt
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • HippoMaps provides an open-source resource for studying the human hippocampus at different scales and with different modalities such as histology, fMRI, structural MRI and EEG.

    • Jordan DeKraker
    • Donna Gift Cabalo
    • Boris C. Bernhardt
    ResearchOpen Access
    Nature Methods
    Volume: 22, P: 2211-2222

  • Therapeutic management of patients with epilepsy is often challenging, particularly in those who are pharmacoresistant. In these patients, the only option to control seizures is elective surgery. Optimization of MRI acquisition sequences might mean early identification of patients, thereby speeding up surgical intervention.

    • Neda Bernasconi
    • Andrea Bernasconi
    News & Views
    Nature Reviews Neurology
    Volume: 10, P: 133-134

  • Drug-resistant focal epilepsy is potentially curable by surgery, but conventional MRI based on visual evaluation is sometimes unable to reveal a lesion for resection. In this Review, Bernasconi and colleagues consider recent advances in brain imaging for the detection of lesions in cases of so-called cryptogenic epilepsy, covering developments in MRI morphometry, computational modeling and diffusion tensor imaging.

    • Andrea Bernasconi
    • Neda Bernasconi
    • Dewi Schrader
    Reviews
    Nature Reviews Neurology
    Volume: 7, P: 99-108

  • Epilepsy is a brain network disorder with associated genetic risk factors. Here, the authors show that spatial patterns of transcriptomic vulnerability co-vary with structural brain network alterations in focal and generalized epilepsy.

    • Sara Larivière
    • Jessica Royer
    • Boris C. Bernhardt
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • Weng et al. harness multimodal neuroimaging and computational modeling to examine whole-brain dysfunction in patients with generalized (GE) and temporal lobe epilepsy (TLE) as well as healthy controls. They find more severe microcircuit and macroscale imbalances in TLE than GE, illustrating the power of this integrated approach.

    • Yifei Weng
    • Sara Larivière
    • Boris C. Bernhardt
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-11