Therapeutic hypothermia is widely recognized to have neuroprotective effects in various clinical settings, from cardiac arrest to traumatic brain injury; however, the practical application of this therapy is not without risk. Choi et al. highlight current methods and protocols of targeted temperature management, and discuss the practical considerations for hypothermia as a therapy for patients with acute brain injury.
- H. Alex Choi
- Neeraj Badjatia
- Stephan A. Mayer