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Showing 1–4 of 4 results
Advanced filters: Author: Negin Rahimzadeh Clear advanced filters

  • The IMEx consortium provides one of the largest resources of curated, experimentally verified molecular interaction data. Here, the authors review how IMEx evolved into a fundamental resource for life scientists and describe how IMEx data can support biomedical research.

    • Pablo Porras
    • Elisabet Barrera
    • Sandra Orchard
    ReviewsOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • There is a lack of blood biomarkers to diagnose glioblastoma (GBM) patients. This retrospective pilot study aims to determine cell-free microRNAs (cfmiRs) in plasma samples from primary and recurrent GBM patients. Thus, 142 plasma and tissue samples were analyzed using the HTG miRNA whole transcriptome assay (WTA). By combining bioinformatic analysis and receiver operating characteristic curves, we showed that cfmiR-3180-3p and cfmiR-5739 have potential utility in primary and recurrent GBM diagnosis.

    • Matias A. Bustos
    • Negin Rahimzadeh
    • Dave S. B. Hoon
    Research
    Laboratory Investigation
    Volume: 102, P: 711-721