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A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis

Neil M O’Brien-Simpson
James A Holden
Eric C Reynolds
ResearchOpen Access01 Dec 2016
npj Vaccines

Volume: 1, P: 1-11
Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

Star-shaped engineered peptide nanoparticles are effective at killing a variety of multidrug-resistant Gram-negative pathogens in vivo with low host toxicity and resistance.

Shu J. Lam
Neil M. O'Brien-Simpson
Greg G. Qiao
Research12 Sept 2016
Nature Microbiology

Volume: 1, P: 1-11
Synthetic peptide branched polymers for antibacterial and biomedical applications

This Review focuses on several facets of synthetic peptide branched polymers including their synthesis, diversity, physicochemical properties and bacteria-killing mechanisms. The current challenges and future applications of synthetic peptide branched polymers in biomedical engineering are highlighted.

Sadegh Shabani
Sara Hadjigol
Greg G. Qiao
Reviews02 Jan 2024
Nature Reviews Bioengineering

Volume: 2, P: 343-361
Label-free macrophage phenotype classification using machine learning methods

Tetiana Hourani
Alexis Perez-Gonzalez
Akram Al-Hourani
ResearchOpen Access30 Mar 2023
Scientific Reports

Volume: 13, P: 1-14
Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis

Vladimir Ilievski
Peter T. Toth
Keiko Watanabe
ResearchOpen Access19 Jun 2020
Scientific Reports

Volume: 10, P: 1-14
Multi-disciplinary approaches paving the way for clinically effective peptide vaccines for cancer

Bansari A. Shah
James A. Holden
Neil M. O’Brien-Simpson
ReviewsOpen Access09 Apr 2025
npj Vaccines

Volume: 10, P: 1-27

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A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis

Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers

Synthetic peptide branched polymers for antibacterial and biomedical applications

Label-free macrophage phenotype classification using machine learning methods

Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis

Multi-disciplinary approaches paving the way for clinically effective peptide vaccines for cancer

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