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Showing 1–2 of 2 results
Advanced filters: Author: Nessim Kichik Clear advanced filters

  • Candida albicans is an opportunistic fungus primarily affecting immunocompromised patients. Here, the authors identify a novel mechanism of host immune stimulation and highlight candidalysin and EGFR signalling components as potential targets for prophylactic and therapeutic intervention of mucosal candidiasis.

    • Jemima Ho
    • Xuexin Yang
    • Julian R. Naglik
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • This study identifies a cytolytic peptide toxin in the opportunistic human fungal pathogen Candida albicans—the peptide is both a crucial virulence factor that permeabilizes the host cell plasma membrane and a key signal that triggers a host danger response pathway.

    • David L. Moyes
    • Duncan Wilson
    • Julian R. Naglik
    Research
    Nature
    Volume: 532, P: 64-68