Lorena Pizarro, Meirav Leibman-Markus et al. explore the genetic mechanisms for plant innate immunity. They functionally characterize a gain of function mutation in SlNRC4a in tomato. They characterize the structure of the mutant protein and functionally demonstrate that it confers broad-spectrum resistance without triggering a hypersensitive response or negatively impacting plant growth and crop yield.
- Lorena Pizarro
- Meirav Leibman-Markus
- Maya Bar