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Showing 1–4 of 4 results
Advanced filters: Author: Neva C. Durand Clear advanced filters

  • We developed PRINT, a computational method that identifies footprints of DNA–protein interactions from bulk and single-cell chromatin accessibility data across multiple scales of protein size.

    • Yan Hu
    • Max A. Horlbeck
    • Jason D. Buenrostro
    ResearchOpen Access
    Nature
    Volume: 638, P: 779-786

  • Analysis of ATAC-seq and RNA-seq data from stimulated T cells identifies genetic variants that disrupt transcription factor binding sites within ATAC-seq peaks. ATAC quantitative trait loci (ATAC-QTLs) are enriched for autoimmune disease-associated variants.

    • Rachel E. Gate
    • Christine S. Cheng
    • Aviv Regev
    Research
    Nature Genetics
    Volume: 50, P: 1140-1150

  • The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

    • Jesse M. Engreitz
    • Heather A. Lawson
    • Ella K. Samer
    Reviews
    Nature
    Volume: 633, P: 47-57