How neural stem cells can transition between states of proliferation and quiescence is unclear. Here, the authors identify Lrig1 as a specific marker for the primed quiescent state and demonstrate that Lrig1 maintains cells in a quiescent state via modulation of the EGFR pathway.
- María Ángeles Marqués-Torrejón
- Charles A. C. Williams
- Steven M. Pollard
