Ribosome ubiquitination regulates HAC1 mRNA processing during the unfolded protein response. Here, the authors show that the SCFGrr1 complex promotes HAC1 mRNA splicing and translation by degrading the deubiquitinating enzyme Ubp3, thereby maintaining eS7A monoubiquitination to facilitate HAC1i translation.
- Nichika Sato
- Yu Nakano
- Toshifumi Inada