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Showing 1–4 of 4 results
Advanced filters: Author: Nicholas H. Angello Clear advanced filters

  • Automated iterative small-molecule synthesis has generally been limited to around one carbon–carbon bond-forming step per day. Now, a next-generation automated synthesizer enables rapid, automated, iterative synthesis of a variety of small molecules. Improvements to chemistry and automation leads to a tenfold decrease in reaction time over previous automated platforms.

    • Wesley Wang
    • Nicholas H. Angello
    • Martin D. Burke
    Research
    Nature Synthesis
    Volume: 3, P: 1031-1038

  • Integration of closed-loop experiments with physics-based feature selection and supervised learning, denoted as closed-loop transfer, yields chemical insights in parallel with optimization of objective functions.

    • Nicholas H. Angello
    • David M. Friday
    • Nicholas E. Jackson
    Research
    Nature
    Volume: 633, P: 351-358

  • Development of organic electronic materials relies on understanding structure-function relationships in conjugated polymers but the synthetic workload to make large numbers of new compounds presents a practical barrier to properly survey conjugated organic derivatives. Here, the authors use automated synthesis to prepare a library of conjugated oligomers with systematically varied side chain composition followed by single-molecule characterization of charge transport.

    • Songsong Li
    • Edward R. Jira
    • Charles M. Schroeder
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8