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Advanced filters: Author: Nicholas M. Chesarino Clear advanced filters

  • The authors report the cryo-EM structure of human A3G bound to HIV-1 Vif, and the hijacked cellular proteins that promote ubiquitin-mediated proteolysis, suggesting how Vif antagonizes A3G by intercepting it to prevent viral restriction.

    • Yen-Li Li
    • Caroline A. Langley
    • John D. Gross
    ResearchOpen Access
    Nature
    Volume: 615, P: 728-733