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Showing 1–4 of 4 results
Advanced filters: Author: Nick G. Hollon Clear advanced filters

  • Ventral pallidum GABA and glutamate neuron activation drives approach and avoidance, respectively. Here, the authors show that both ventral pallidum cell types are activated during approach to reward and by aversive stimuli, but elicit opponent effects on VTA cell-type activity.

    • Lauren Faget
    • Lucie Oriol
    • Thomas S. Hnasko
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • In rats, individual differences in risk preference and in sensitivity to gains compared with losses are controlled by a specific neuronal population, stimulation of which neutralizes risk-seeking behaviour. See Letter p.642

    • Nick G. Hollon
    • Paul E. M. Phillips
    News & Views
    Nature
    Volume: 531, P: 588-589

  • In this Review, Hollon, Burgeno and Phillips discuss recent studies providing mechanistic insight into how stress alters circuitry involved in reward-related learning and motivation, as well as work examining how acute and chronic stress affect action selection in both rodents and humans.

    • Nick G Hollon
    • Lauren M Burgeno
    • Paul E M Phillips
    Reviews
    Nature Neuroscience
    Volume: 18, P: 1405-1412

  • The neuropeptide corticotropin-releasing factor (CRF) acts in the nucleus accumbens of mice to increase dopamine release through coactivation of CRF receptor 1 (CRFR1) and CRFR2, but exposure to severe stress results in loss of this regulation and a switch in the reaction to CRF from appetitive to aversive.

    • Julia C. Lemos
    • Matthew J. Wanat
    • Paul E. M. Phillips
    Research
    Nature
    Volume: 490, P: 402-406