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Cognitive and global morphometry trajectories as predictors of persistent distressing psychotic-like experiences in youth

Karcher et al. use data from the Adolescent Brain Cognitive Development Study to explore how changes in cognition and brain structure influence the relationship between risk factors and persistent distressing psychotic-like experiences in children aged 9–13 years.

Nicole R. Karcher
Fanghong Dong
Deanna M. Barch
Research12 Aug 2025
Nature Mental Health

Volume: 3, P: 1012-1019
Mapping multimodal risk factors to mental health outcomes

In this study, Jirsaraie et al. analyze data from the Adolescent Brain Cognitive Developmental study and use machine learning to predict both current and future psychological symptoms and to determine rates of change in symptom severity over time.

Robert J. Jirsaraie
Deanna M. Barch
Nicole R. Karcher
Research15 Sept 2025
Nature Mental Health

Volume: 3, P: 1230-1240
Associations between Electrophysiological Evidence of Reward and Punishment-Based Learning and Psychotic Experiences and Social Anhedonia in At-Risk Groups

Nicole R Karcher
Bruce D Bartholow
John G Kerns
Research15 Sept 2016
Neuropsychopharmacology

Volume: 42, P: 925-932
A phenome-wide association study of cross-disorder genetic liability in youth genetically similar to individuals from European reference populations

Using an exploratory phenome-wide association study of polygenic risk scores (PRS) in children aged 9–13 from the Adolescent Brain Cognitive Development Study cohort, the authors identify neurodevelopmental and internalizing PRS associations with multiple phenotypes similar to the constituent GWAS indicators (for example, neurodevelopmental and internalizing traits) as well as cross-trait phenotypes (for example, screen time, cortical volume).

Sarah E. Paul
Sarah M. C. Colbert
Nicole R. Karcher
Research14 Oct 2024
Nature Mental Health

Volume: 2, P: 1327-1341
Publisher Correction: Perinatal insult dimensions and developmental trajectories of psychotic-like experiences

Eric R. Larson
Nicole R. Karcher
Alexandra B. Moussa-Tooks
Amendments and CorrectionsOpen Access20 Nov 2025
Schizophrenia

Volume: 11, P: 1
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Using a sample of more than 1 million individuals, Hatoum et al. identify genomic loci associated with general and substance-specific addiction risk.

Alexander S. Hatoum
Sarah M. C. Colbert
Arpana Agrawal
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 210-223
Attention-mediated genetic influences on psychotic symptomatology in adolescence

Using data from the Adolescent Brain Cognitive Development Study, the authors find an association between neuropsychiatric and cognitive polygenic scores and psychotic-like experience severity, and reveal a mediating role of attentional variability.

Sarah E. Chang
Dylan E. Hughes
Carrie E. Bearden
Research28 Oct 2024
Nature Mental Health

Volume: 2, P: 1518-1531
Perinatal insult dimensions and developmental trajectories of psychotic-like experiences

Eric R. Larson
Nicole R. Karcher
Alexandra B. Moussa-Tooks
ResearchOpen Access25 Aug 2025
Schizophrenia

Volume: 11, P: 1-10
Qualitative data sharing and synthesis for sustainability science

Opportunities, challenges and recommended targeted actions to accelerate qualitative data sharing to address complex socio–environmental problems

Steven M. Alexander
Kristal Jones
Nic Weber
Reviews25 Nov 2019
Nature Sustainability

Volume: 3, P: 81-88
Associations between social behaviors and experiences with neural correlates of implicit emotion regulation in middle childhood

Keara C. Geckeler
Deanna M. Barch
Nicole R. Karcher
Research08 Feb 2022
Neuropsychopharmacology

Volume: 47, P: 1169-1179
Persistent and distressing psychotic-like experiences using adolescent brain cognitive development℠ study data

Nicole R. Karcher
Rachel L. Loewy
Deanna M. Barch
Research16 Nov 2021
Molecular Psychiatry

Volume: 27, P: 1490-1501
Striatum-related functional activation during reward- versus punishment-based learning in psychosis risk

Nicole R. Karcher
Jessica P. Y. Hua
John G. Kerns
Research04 Jul 2019
Neuropsychopharmacology

Volume: 44, P: 1967-1974
The ABCD study: understanding the development of risk for mental and physical health outcomes

Nicole R. Karcher
Deanna M. Barch
Reviews15 Jun 2020
Neuropsychopharmacology

Volume: 46, P: 131-142

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