Mensah, Efthymiou, Mureanu, and Monreal et al. examine RNA transcripts from over 40,000 CD4+ T cells to investigate regulatory T cell states in patients with gestational diabetes mellitus (GDM). GDM was associated with the abundance of memory CD4+ T cells and altered expression within naive and effector Treg subsets with aberrant genes serving to identify GDM from whole blood mRNA datasets.
- Nana E. Mensah
- Athina Efthymiou
- Panicos Shangaris