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Showing 1–13 of 13 results
Advanced filters: Author: Niels Johan Christensen Clear advanced filters

  • Meta-analyses in up to 1.3 million individuals identify 87 rare-variant associations with blood pressure traits. On average, rare variants exhibit effects ~8 times larger than the mean effects of common variants and implicate candidate causal genes at associated regions.

    • Praveen Surendran
    • Elena V. Feofanova
    • Joanna M. M. Howson
    Research
    Nature Genetics
    Volume: 52, P: 1314-1332

  • Denoising low-counting statistics data in the presence of multiple, unknown noise profiles is a challenging task in scientific applications where high accuracy is required. Oppliger and colleagues train a deep convolutional neural network on pairs of experimental low- and high-noise X-ray diffraction data and demonstrate better performance on experimental noise filtering compared with the case of training on artificial data pairs.

    • Jens Oppliger
    • M. Michael Denner
    • Johan Chang
    ResearchOpen Access
    Nature Machine Intelligence
    Volume: 6, P: 180-186

  • Peptide and oligonucleotide systems are known to self-assemble both in nature and artificial systems. Here, the authors combine both forms of self-assembly through the synthesis of peptideoligonucleotide conjugates and show formation of a three-helix structure that dimerises at higher concentrations.

    • Chenguang Lou
    • Manuel C. Martos-Maldonado
    • Knud J. Jensen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9

  • Chiral communication can propagate in secondary structures within the effective intermolecular force (IMF) range but it is not known whether long-range chiral communication exists between tertiary peptide structures. Here, the authors use single-molecule force spectroscopy to investigate chiral interaction between DNA duplexes/triplexes and peptide coiled-coils and demonstrate chiral communication beyond the IMF distance.

    • Shankar Pandey
    • Shankar Mandal
    • Hanbin Mao
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • Observations from the JWST of the second brightest GRB ever detected, GRB 230307A, indicate that it belongs to the class of long-duration GRBs resulting from compact object mergers, with the decay of lanthanides powering the longlasting optical and infrared emission.

    • Andrew J. Levan
    • Benjamin P. Gompertz
    • David Alexander Kann
    ResearchOpen Access
    Nature
    Volume: 626, P: 737-741

  • An individual star at z = 1.49 is gravitationally lensed and highly magnified by a foreground galaxy cluster. Fluctuations in the star’s emission provide insight on the mass function of intracluster stars, compact objects and the presence of dark-matter subhaloes.

    • Patrick L. Kelly
    • Jose M. Diego
    • Benjamin J. Weiner
    Research
    Nature Astronomy
    Volume: 2, P: 334-342

  • Far-infrared measurements of galaxies in the early Universe would reveal their detailed properties, but have been lacking for the more typical galaxies where most stars form; here an archetypal, early Universe star-forming galaxy is detected at far-infrared wavelengths, allowing its dust mass, total star-formation rate and dust-to-gas ratio to be calculated.

    • Darach Watson
    • Lise Christensen
    • Michał Jerzy Michałowski
    Research
    Nature
    Volume: 519, P: 327-330

  • While it is widely believed that high-temperature superconductivity in cuprate materials arises from an intertwined interplay between charge and spin fluctuations, the microscopic coupling between charge and spin degrees of freedom still remains a mystery in these materials. Here, the authors profit from neutron scattering with superior beam focusing to probe the subtle spin-density wave order under uniaxial pressure, and demonstrate that charge and spin orders respond to the external tuning parameter in the same manner.

    • Gediminas Simutis
    • Julia Küspert
    • Daniel G. Mazzone
    ResearchOpen Access
    Communications Physics
    Volume: 5, P: 1-7