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Showing 1–5 of 5 results
Advanced filters: Author: Niki M. Moutsopoulos Clear advanced filters

  • The secretory functions of the exocrine glands are impaired in patients with Sjögren's syndrome, resulting in symptoms of dry eyes and dry mouth. This Review discusses the currently available treatments for the glandular and extraglandular manifestations of this chronic autoimmune disorder, and describes potential future therapies.

    • Clio P Mavragani
    • Niki M Moutsopoulos
    • Haralampos M Moutsopoulos
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 2, P: 252-261

  • DEL-1 protein interferes with leukocyte adhesion to prevent inflammation. Chavakis and colleagues now show that DEL-1 contributes to tissue resolution after inflammation by promoting macrophage-mediated efferocytosis and M2-like pro-resolving activities.

    • Ioannis Kourtzelis
    • Xiaofei Li
    • Triantafyllos Chavakis
    Research
    Nature Immunology
    Volume: 20, P: 40-49

  • The oral mucosa is a critical barrier tissue that is continually exposed to pathogens, but antiviral immune responses in this tissue are poorly understood. Moreover, recent viral outbreaks, including SARS-CoV-2 and mpox, feature oral symptoms. This Review discusses antiviral immunity in the oral cavity and presents current mouse models for the study of oral viral infections.

    • Heather D. Hickman
    • Niki M. Moutsopoulos
    Reviews
    Nature Reviews Immunology
    Volume: 25, P: 235-249