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Showing 1–2 of 2 results
Advanced filters: Author: Nikita Isima Clear advanced filters

  • EGFR inhibition and lenvatinib treatment of liver cancer cells in vitro and in in vivo mouse models has potent anti-proliferative effects, and lenvatinib plus gefitinib treatment of 12 patients with advanced liver cancer resulted in meaningful clinical responses.

    • Haojie Jin
    • Yaoping Shi
    • René Bernards
    Research
    Nature
    Volume: 595, P: 730-734

  • Epigenetic changes are a driver of senescence and occur during aging. A study in Nature Aging shows how chromatin-mediated loss of transcription fidelity, previously shown in yeast and worms, also occurs in mammalian cells and could constitute a new hallmark of senescence and aging.

    • Nikita Isima
    • Jesús Gil
    News & Views
    Nature Aging
    Volume: 3, P: 374-375