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Advanced filters: Author: Niloufar Monhasery Clear advanced filters

  • The expression of oncogenic MYC paralogs in small cell lung cancer is mutually exclusive. In this study, the authors show that MYC, but not MYCN or MYCL, represses BCL2, resulting in cells that are uniquely sensitive to apoptosis, and find that CHK1 and AURKA inhibitors may be useful for treating these cancers.

    • Marcel A. Dammert
    • Johannes Brägelmann
    • Martin L. Sos
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11