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Showing 1–2 of 2 results
Advanced filters: Author: Nils L. Visser Clear advanced filters

  • Tumour-reactive CD8+ T cells are enriched in functional clusters with tumour cells and/or antigen-presenting cells and can be isolated and expanded from clinical samples.

    • Sofía Ibáñez-Molero
    • Johanna Veldman
    • Daniel S. Peeper
    ResearchOpen Access
    Nature
    Volume: 649, P: 467-476

  • The IFNγ response pathway is associated with response to immunotherapy in cancer. Here the authors show that high levels of the IFNγ-receptor (IFNγ-R1) affect the outcome of immunotherapy in a context-dependent fashion and identify the E3 ubiquitin ligase STUB1 as a negative regulator of IFNγ-R1/JAK1 expression in cancer cells.

    • Georgi Apriamashvili
    • David W. Vredevoogd
    • Daniel S. Peeper
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16