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Showing 1–2 of 2 results
Advanced filters: Author: Nina Henriette Uhlenhaut Clear advanced filters

  • BMAL1–HIF2α heterodimer was recently shown to modulate circadian variations in myocardial injury. Here, the authors show that BMAL1 can form a heterodimer with HIF2α in clear cell renal cell carcinoma, contributing to tumor progression and response to HIF2α antagonist drugs.

    • Rebecca M. Mello
    • Diego Gomez Ceballos
    • Katja A. Lamia
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • Menopause is associated with metabolic changes and an increased risk of a number of chronic diseases. Here, the authors show in a mouse model of menopause that an amino acid-enriched diet rescues liver lipid metabolism and prevents weight gain in a manner dependent on hepatic ERα.

    • Sara Della Torre
    • Valeria Benedusi
    • Adriana Maggi
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13