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Showing 1–2 of 2 results
Advanced filters: Author: Nina Salustros Clear advanced filters

  • P1B-type ATPases export excess transition metals from cells. Here, the authors report a molecular structure of CopA, a coppertransporting P1B-ATPase from A. fulgidus, in an inward-facing E1 conformation.

    • Nina Salustros
    • Christina Grønberg
    • Pontus Gourdon
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • In human cells, P5B‐ATPases execute export of spermine from lysosomes to the cytosol, but the mechanisms of spermine recognition, uptake and transport remain elusive. Here the authors present cryo‐EM structures of a yeast homolog of human ATP13A2‐5, Ypk9, which depict three separate transport cycle intermediates, including spermine‐bound conformations

    • Ping Li
    • Kaituo Wang
    • Pontus Gourdon
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-8