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Showing 1–4 of 4 results
Advanced filters: Author: Niyati Lobo Clear advanced filters

  • Surgical menopause occurs in premenopausal women who undergo radical cystectomy with bilateral oophorectomy to treat bladder cancer. This Review discusses the pathophysiology of surgical menopause in these patients and highlights current strategies to mitigate associated symptoms and long-term health risks.

    • Elizabeth Day
    • Francesco Pio Bizzarri
    • Niyati Lobo
    Reviews
    Nature Reviews Urology
    P: 1-11

  • Muscle-invasive bladder cancer (MIBC) is an aggressive disease associated with high morbidity and mortality. In this Perspective, the authors describe the timeline of advances in treating MIBC, including radical cystectomy with pelvic lymph node dissection, the creation of increasingly sophisticated urinary diversions, use of cisplatin-based neoadjuvant chemotherapy, bladder-sparing protocols, and immunotherapy.

    • Niyati Lobo
    • Chloe Mount
    • Muhammad Shamim Khan
    Reviews
    Nature Reviews Urology
    Volume: 14, P: 565-574

  • Radical cystectomy and urinary diversion is the gold-standard treatment for muscle-invasive and high-risk non-muscle-invasive bladder cancer. Ureteroenteric anastomotic stricture has a reported prevalence of up to 10%, and such strictures have serious consequences that can lead to loss of kidney function and infectious complications. Here, the authors discuss the pathophysiology, diagnosis, risk factors, and management of ureteroenteric anastomotic strictures and describe ways in which stricture risk can be minimized.

    • Niyati Lobo
    • Sophie Dupré
    • Muhammad Shamim Khan
    Reviews
    Nature Reviews Urology
    Volume: 13, P: 447-455

  • Bacillus Calmette–Guérin (BCG) has been used to prevent tuberculosis for a century and is also a standard approach for the treatment of non-muscle-invasive bladder cancer. However, BCG also has a plethora of non-specific effects that occur via the induction of trained immunity and have raised the hypothesis that BCG vaccination could be used to protect against coronavirus disease 2019 (COVID-19). In this Perspective, the authors describe the history of BCG, discuss the mechanisms of its effects, and consider its potential role during the COVID-19 pandemic.

    • Niyati Lobo
    • Nathan A. Brooks
    • Ashish M. Kamat
    Reviews
    Nature Reviews Urology
    Volume: 18, P: 611-622