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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Felicia N. Watson
Melanie J. Shears
Sean C. Murphy
ResearchOpen Access04 Feb 2024
Scientific Reports

Volume: 14, P: 1-16
Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron

Sera from unvaccinated, vaccinated, and previously infected and vaccinated individuals show reduced neutralizing and spike protein-binding activity towards the Omicron (B.1.1.529) variant of SARS-CoV-2 compared to other variants.

Juan Manuel Carreño
Hala Alshammary
Florian Krammer
Research31 Dec 2021
Nature

Volume: 602, P: 682-688
Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage

Development of broadly neutralizing antibodies (bnAb) against HIV-1 in infected adults is a multi-step process unachievable by current vaccine approaches. Here the authors reconstruct the ontogeny of an infant bnAb, which develops in fewer steps, and identify its unique features that may shorten the path to HIV vaccines.

Cassandra A. Simonich
Laura Doepker
Julie Overbaugh
ResearchOpen Access16 May 2019
Nature Communications

Volume: 10, P: 1-12
Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

Alison Roth
Steven P. Maher
John H. Adams
Amendments and CorrectionsOpen Access08 Jun 2018
Nature Communications

Volume: 9, P: 1
A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

Currently available platforms to study liver stage of Plasmodium species have limitations. Here, the authors show that primary human hepatocyte cultures in 384-well format support hypnozoite and other liver stage development and are suitable for drug and antibody screens.

Alison Roth
Steven P. Maher
John H. Adams
ResearchOpen Access09 May 2018
Nature Communications

Volume: 9, P: 1-16
Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies

Brandon K. Wilder
Vladimir Vigdorovich
D. Noah Sather
ResearchOpen Access26 May 2022
npj Vaccines

Volume: 7, P: 1-13
Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP

Ryan W. J. Steel
Vladimir Vigdorovich
Stefan H. I. Kappe
ResearchOpen Access31 May 2021
Scientific Reports

Volume: 11, P: 1-11
Identifying Plasmodium P36 and P52 antigens for coadministration with circumsporozoite protein to enhance vaccine efficacy

Naveen Yadav
Anya C. Kalata
Sean C. Murphy
ResearchOpen Access06 Dec 2024
npj Vaccines

Volume: 9, P: 1-12

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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron

Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage

Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies

Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP

Identifying Plasmodium P36 and P52 antigens for coadministration with circumsporozoite protein to enhance vaccine efficacy

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