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Showing 1–7 of 7 results
Advanced filters: Author: Noam Steinberg Clear advanced filters

  • Ionescu, Ankol et al. show that, in ALS mouse and iPSC models, TDP-43 aggregation at NMJs stems from aberrant axonal translation, normally repressed by muscle EV-derived miR126. Loss of miR126 in ALS increases TDP-43 buildup, impairs local synthesis and triggers degeneration.

    • Ariel Ionescu
    • Lior Ankol
    • Eran Perlson
    ResearchOpen Access
    Nature Neuroscience
    Volume: 28, P: 2201-2216

  • The levels of 1,251 metabolites are measured in 475 phenotyped individuals, and machine-learning algorithms reveal that diet and the microbiome are the determinants with the strongest predictive power for the levels of these metabolites.

    • Noam Bar
    • Tal Korem
    • Eran Segal
    Research
    Nature
    Volume: 588, P: 135-140

  • Here the authors provide immunogenicity and efficacy data at 3-month follow-up for vaccinees who have received a fourth dose of either mRNA1273 or BNT162b2. Both vaccines were highly effective against substantial symptomatic disease, but had little effect against SARS-CoV-2 infection.

    • Michal Canetti
    • Noam Barda
    • Gili Regev-Yochay
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • The authors analyzed data from a deeply phenotyped longitudinal cohort to uncover sex-specific aging patterns. They found that biological age scores, derived from diverse biomarkers, correlate with age-related diseases, providing insights for personalized medical interventions.

    • Lee Reicher
    • Noam Bar
    • Eran Segal
    Research
    Nature Aging
    Volume: 4, P: 1643-1655

  • Statistical analyses of a metagenomics-sequenced human cohort identify a relatively minor role for genetics in determining microbiome composition and show that several human phenotypes are as strongly associated with the gut microbiome as with host genetics.

    • Daphna Rothschild
    • Omer Weissbrod
    • Eran Segal
    Research
    Nature
    Volume: 555, P: 210-215