Nature Search

mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress

The authors showed that mGluR5 can upregulate the expression of ΔFosB, a resilience molecule, in the nucleus accumbens. In stress-induced animal models of depression, mGluR5-induced upregulation of ΔFosB in the nucleus accumbens enhances resilience to stress.

Sora Shin
Obin Kwon
Dong Goo Kim
Research25 May 2015
Nature Neuroscience

Volume: 18, P: 1017-1024
An update in the treatment preference for hyperthyroidism

Obin Kwon
Correspondence17 May 2018
Nature Reviews Endocrinology

Volume: 14, P: 438
Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure

Nicotinamide phosphoribosyl transferase (NAMPT) is a critical regulator of cellular nicotinamide adenine dinucleotide (NAD)⁺ levels. Here, the authors show that blood NAMPT contributes to the circadian rhythm generation of locomotor activity and energy expenditure by regulating hypothalamic NAD⁺ levels.

Jae Woo Park
Eun Roh
Min-Seon Kim
ResearchOpen Access08 Apr 2023
Nature Communications

Volume: 14, P: 1-17
Hypothalamic control of energy expenditure and thermogenesis

Le Trung Tran
Sohee Park
Obin Kwon
ReviewsOpen Access17 Mar 2022
Experimental & Molecular Medicine

Volume: 54, P: 358-369
Enhanced neuronal activity by suffruticosol A extracted from Paeonia lactiflora via partly BDNF signaling in scopolamine-induced memory-impaired mice

June Hee Kim
Young-Eun Han
Min Soo Kim
ResearchOpen Access20 Jul 2023
Scientific Reports

Volume: 13, P: 1-14
Sex-specific bi‑directional association between osteoporosis and depression from the national representative data of South Korea

Min Kyoung Shin
Hyejin Kim
Obin Kwon
ResearchOpen Access09 Jun 2022
Scientific Reports

Volume: 12, P: 1-10
Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types

Jaeik Oh
Chanwoong Hwa
Sung-Yup Cho
ResearchOpen Access06 Jul 2022
Experimental & Molecular Medicine

Volume: 54, P: 906-921

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mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress

An update in the treatment preference for hyperthyroidism

Circulating blood eNAMPT drives the circadian rhythms in locomotor activity and energy expenditure

Hypothalamic control of energy expenditure and thermogenesis

Enhanced neuronal activity by suffruticosol A extracted from Paeonia lactiflora via partly BDNF signaling in scopolamine-induced memory-impaired mice

Sex-specific bi‑directional association between osteoporosis and depression from the national representative data of South Korea

Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types

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