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Showing 1–2 of 2 results
Advanced filters: Author: Okuto Shounai Clear advanced filters

  • How translation affects ribosome stability is an intriguing question. Here, the authors uncover a collision-induced small subunit turnover pathway that selectively removes suboptimal ribosomes during ribosome competition and alters subunit abundance under stress-related translational perturbations.

    • Sihan Li
    • Okuto Shounai
    • Toshifumi Inada
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • Identification of SDD1 mRNA from Saccharomyces cerevisiae as an endogenous RQC substrate allows analysis of the mechanism underlying translational stalling and Hel2-dependent polyubiquitination of collided ribosomes to provide insight into ribosome dissociation.

    • Yoshitaka Matsuo
    • Petr Tesina
    • Toshifumi Inada
    Research
    Nature Structural & Molecular Biology
    Volume: 27, P: 323-332