Nature Search

Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity

Olga V Volpert
Kristina M Dameron
Noël Bouck
Research27 Mar 1997
Oncogene

Volume: 14, P: 1495-1502
Maspin is an angiogenesis inhibitor

Ming Zhang
Olga Volpert
Noël Bouck
Research01 Feb 2000
Nature Medicine

Volume: 6, P: 196-199
Vascular heterogeneity of tight junction Claudins guides organotropic metastasis

Kalluri and colleagues use mammary carcinoma models to study the causes of metastatic organotropism and find an organ-specific role for angiopoietin 2 in driving lung metastasis through the suppression of the tight junction protein Claudin 5.

Xunian Zhou
Valerie S. LeBleu
Raghu Kalluri
Research17 Sept 2024
Nature Cancer

Volume: 5, P: 1371-1389
Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

Benilde Jiménez
Olga V. Volpert
Noël Bouck
Research01 Jan 2000
Nature Medicine

Volume: 6, P: 41-48
c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1

Benilde Jiménez
Olga V Volpert
Noël Bouck
Research22 Jun 2001
Oncogene

Volume: 20, P: 3443-3448
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium–derived factor

Olga V. Volpert
Tetiana Zaichuk
Noel P. Bouck
Research01 Apr 2002
Nature Medicine

Volume: 8, P: 349-357
1α,25-Dihydroxyvitamin D₃ regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells

Nuria Isabel Fernandez-Garcia
Hector G Palmer
Benilde Jimenez
Research11 Jul 2005
Oncogene

Volume: 24, P: 6533-6544
Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

Exosomes are extracellular vesicles that can favor tumor development and metastasis. Here, the authors show that cancer exosomes may also exert a suppressive function; in fact, exosomes from non-metastatic melanoma cells can lead to the recruitment of patrolling monocytes, which clear cancer cells at the pre-metastatic niche.

Michael P. Plebanek
Nicholas L. Angeloni
Olga V. Volpert
ResearchOpen Access06 Nov 2017
Nature Communications

Volume: 8, P: 1-12
Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1

Nicholas L. Angeloni
Kaylin M. McMahon
C. Shad Thaxton
ResearchOpen Access11 Mar 2016
Scientific Reports

Volume: 6, P: 1-13
Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake

Michael P. Plebanek
R. Kannan Mutharasan
C. Shad Thaxton
ResearchOpen Access29 Oct 2015
Scientific Reports

Volume: 5, P: 1-14
Targeting the ANGPT–TIE2 pathway in malignancy

The ANGPT–TIE2 pathway is important for angiogenesis, lymphangiogenesis and inflammation, and therefore has important roles in cancer. Given the context-dependent and opposing effects of the ANGPTs, how do we target this pathway?

Hanhua Huang
Abhijit Bhat
Rodney Lappe
Reviews01 Aug 2010
Nature Reviews Cancer

Volume: 10, P: 575-585

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Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity

Maspin is an angiogenesis inhibitor

Vascular heterogeneity of tight junction Claudins guides organotropic metastasis

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1

Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium–derived factor

1α,25-Dihydroxyvitamin D₃ regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells

Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche

Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1

Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake

Targeting the ANGPT–TIE2 pathway in malignancy

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