Reactive oxygen species (ROS), such as hydrogen peroxide, play a key role in cellular processes but can cause damage at high concentrations. The authors demonstrate that elevated ROS levels are accompanied by an increased cell stiffness that is explained by cytosolic acidification due to lysosomal degradation and not by alterations in the cytoskeleton.
- Yesaswini Komaragiri
- Ricardo Hugo Pires
- Oliver Otto