Interaction of alpha-synuclein (aSyn) with physiological lipid membranes leads to the disintegration of membranes, incorporation of lipids by aSyn fibrils, increased aggregation rate of aSyn fibrils, and increased uptake of lipid-associated fibrils compared to aSyn only fibrils into neurons.
- Amberley D. Stephens
- Ana Fernandez Villegas
- Gabriele S. Kaminski Schierle