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Showing 1–2 of 2 results
Advanced filters: Author: Onur Yukselen Clear advanced filters
  • Dissecting the causal relationship between genotype and phenotype can be challenging, Here, the authors develop Worm Perturb-Seq, a high throughput sequencing and analytical framework to assess transcriptomic changes upon gene perturbation in whole C. elegans.

    • Hefei Zhang
    • Xuhang Li
    • Albertha J. M. Walhout
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-21
  • The feasibility of adeno-associated-virus-delivered nonsense suppressor tRNAs operating on premature termination codons (AAV-NoSTOP) is explored to restore gene function, using a mouse model of mucopolysaccharidosis type I for proof of concept.

    • Jiaming Wang
    • Yue Zhang
    • Dan Wang
    Research
    Nature
    Volume: 604, P: 343-348