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Showing 1–9 of 9 results
Advanced filters: Author: Oren Amsalem Clear advanced filters

  • Realistic simulations of neurons and neural networks are key for understanding neural computations. Here the authors describe Neuron_Reduce, an analytic approach to simplify neurons receiving thousands of synapses and accelerate their simulations by 40–250 folds, while preserving voltage dynamics and dendritic computations.

    • Oren Amsalem
    • Guy Eyal
    • Idan Segev
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Here, using data from a competition between academic teams to influence decision-making, the authors show that people, intending to maximize their profit, prefer options delivering rewards in a discoverable pattern, even when such a preference proves costly.

    • Haran Shani-Narkiss
    • Baruch Eitam
    • Oren Amsalem
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • A quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in fetal and paediatric thymic development.

    • Nadav Yayon
    • Veronika R. Kedlian
    • Sarah A. Teichmann
    ResearchOpen Access
    Nature
    Volume: 635, P: 708-718

  • The dorsal pons in the brainstem is packed with clusters of neurons, including the parabrachial nucleus, that are involved in many vital functions. Here, authors use single nucleus RNA sequencing and MERFISH to create a spatially defined transcriptional atlas of this region.

    • Stefano Nardone
    • Roberto De Luca
    • Bradford B. Lowell
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21

  • Whether the cortex operates in a fluctuation-driven regime remains unclear. Here, the authors found that standard models explain spiking but not sub-threshold statistics; however, this was resolved by adding dendritic morphology, suggesting a functional role for dendrites in decision-making.

    • Oren Amsalem
    • Hidehiko Inagaki
    • Ran Darshan
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Offline cortical reactivations predict the gradual drift and separation in sensory cortical response patterns and may enhance sensory discrimination.

    • Nghia D. Nguyen
    • Andrew Lutas
    • Mark L. Andermann
    Research
    Nature
    Volume: 625, P: 110-118

  • The study of learning algorithms in the neocortex requires comprehensive knowledge of synaptic plasticity between its diverse cell types, which is currently lacking. Chindemi et al. describe a modeling approach to fill these gaps in experimental literature, and predict the features of synaptic plasticity in vivo.

    • Giuseppe Chindemi
    • Marwan Abdellah
    • Eilif B. Muller
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-19

  • In two mouse models of intestinal cancer, mutant p53 has an oncogenic effect in the distal gut but a tumour-suppressive effect in the proximal gut, and these opposing properties are determined by the gut microbiome.

    • Eliran Kadosh
    • Irit Snir-Alkalay
    • Yinon Ben-Neriah
    Research
    Nature
    Volume: 586, P: 133-138