Nature Search

Correction: Corrigendum: Sex-specific transcriptional signatures in human depression

Benoit Labonté
Olivia Engmann
Eric J Nestler
Amendments and Corrections01 Apr 2018
Nature Medicine

Volume: 24, P: 525
Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Hope Kronman
Angélica Torres-Berrío
Eric J. Nestler
Amendments and Corrections08 Apr 2021
Nature Neuroscience

Volume: 24, P: 753-754
Determining the role of microRNAs in psychiatric disorders

Several psychiatric disorders have been linked to changes in microRNA levels in the circulation and brain. In this Review, Issler and Chen discuss approaches for studying the role of these non-coding RNAs in disease and highlight examples of their potential pathophysiological contributions to psychiatric disorders.

Orna Issler
Alon Chen
Reviews20 Mar 2015
Nature Reviews Neuroscience

Volume: 16, P: 201-212
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex

Researchers identify a transcriptional network engaged in stress-resilient mice that is regulated by a previously unstudied transcription factor, Zfp189, and elucidate molecular mechanisms controlling this network and resilience behavior.

Zachary S. Lorsch
Peter J. Hamilton
Eric J. Nestler
Research19 Aug 2019
Nature Neuroscience

Volume: 22, P: 1413-1423
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Early life stress (ELS) promotes susceptibility to the effects of chronic stress in adulthood. Kronman et al. show that ELS alters H3K79me2 in D2 medium spiny neurons in the nucleus accumbens and that this underlies the susceptibility to the effects of subsequent stress.

Hope Kronman
Angélica Torres-Berrío
Eric J. Nestler
Research15 Mar 2021
Nature Neuroscience

Volume: 24, P: 667-676
Estrogen receptor α drives pro-resilient transcription in mouse models of depression

Stress resilience is accompanied by broad changes in gene expression. This study shows that estrogen receptor α (ERα) is a key upstream regulator of these changes in the nucleus accumbens, and that overexpression of ERα increases behavioral resilience via a sex-specific transcriptional mechanism.

Zachary S. Lorsch
Yong-Hwee Eddie Loh
Eric J. Nestler
ResearchOpen Access16 Mar 2018
Nature Communications

Volume: 9, P: 1-11
Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression

Yentl Y. van der Zee
Lars M. T. Eijssen
Orna Issler
Research28 Jul 2022
Molecular Psychiatry

Volume: 27, P: 4536-4549
Sex-specific transcriptional signatures in human depression

Brain-region-specific RNA-seq from humans with major depressive disorder reveals unique transcriptomic profiles in males and females, with little overlap.

Benoit Labonté
Olivia Engmann
Eric J Nestler
Research21 Aug 2017
Nature Medicine

Volume: 23, P: 1102-1111
Male and female behavioral variability and morphine response in C57BL/6J, DBA/2J, and their BXD progeny following chronic stress exposure

Carole Morel
Lyonna F. Parise
Ming-Hu Han
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
Gadd45b mediates depressive-like role through DNA demethylation

Benoit Labonté
Yun Ha Jeong
Ja Wook Koo
ResearchOpen Access15 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine

Drew D. Kiraly
Deena M. Walker
Eric J. Nestler
ResearchOpen Access18 Oct 2016
Scientific Reports

Volume: 6, P: 1-12
Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

Jian Feng
Catherine J Pena
Eric J Nestler
Research11 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1657-1669

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Correction: Corrigendum: Sex-specific transcriptional signatures in human depression

Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Determining the role of microRNAs in psychiatric disorders

Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex

Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Estrogen receptor α drives pro-resilient transcription in mouse models of depression

Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression

Sex-specific transcriptional signatures in human depression

Male and female behavioral variability and morphine response in C57BL/6J, DBA/2J, and their BXD progeny following chronic stress exposure

Gadd45b mediates depressive-like role through DNA demethylation

Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

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