The bile ducts of the liver form a network of large ducts and small ductules, though how they are patterned remains unclear. Hrncir et al. show that Sox9 is required for the morphogenesis of small intrahepatic bile ductules in mice, highlighting distinct genetic requirements that drive bile duct heterogeneity.
- Hannah R. Hrncir
- Brianna Goodloe
- Adam D. Gracz
