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Advanced filters: Author: Otmar Schaaf Clear advanced filters

  • A non-covalent inhibitor that binds preferentially to the inactive state of KRAS while sparing NRAS and HRAS is reported, indicating that most KRAS oncoproteins cycle between an active state and an inactive state in cancer cells.

    • Dongsung Kim
    • Lorenz Herdeis
    • Piro Lito
    ResearchOpen Access
    Nature
    Volume: 619, P: 160-166