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Showing 1–4 of 4 results

Advanced filters: Author: Ozlem Yedier-Bayram Clear advanced filters

Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis

Through genome-wide and focused CRISPR screens, Zhang et al. discover that loss of PRC2 or KMT2D-COMPASS enables distinct EMT trajectories, which exert differential effects on the metastatic capability of carcinoma cells.

Yun Zhang
Joana Liu Donaher
Robert A. Weinberg
Research11 Apr 2022
Nature Cell Biology

Volume: 24, P: 554-564
Chromatin-focused genetic and chemical screens identify BRPF1 as a targetable vulnerability in Taxol-resistant triple-negative breast cancer

Ozlem Yedier-Bayram
Ahmet Cingöz
Tugba Bagci-Onder
ResearchOpen Access30 Jun 2025
Experimental & Molecular Medicine

Volume: 57, P: 1294-1307
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities

Ozlem Yedier-Bayram
Bengul Gokbayrak
Tugba Bagci-Onder
ResearchOpen Access16 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-11
Exploiting epigenetic targets to overcome taxane resistance in prostate cancer

Buse Cevatemre
Ipek Bulut
Ceyda Acilan
ResearchOpen Access12 Feb 2024
Cell Death & Disease

Volume: 15, P: 1-14