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Showing 1–3 of 3 results
Advanced filters: Author: Pablo De Ioannes Clear advanced filters

  • Cryo-electron microscopy and biochemical studies elucidate the read–write mechanisms of non-canonical PRC1-containing RYBP in histone H2A lysine 119 monoubiquitination and their roles in maintaining epigenetic inheritance.

    • Victoria Godínez López
    • Marco Igor Valencia-Sánchez
    • Karim-Jean Armache
    Research
    Nature
    Volume: 636, P: 755-761

  • The Origin Recognition Complex (ORC) plays conserved and diverse roles in eukaryotes. Here the authors present the structure of a chromatin interacting domain of yeast Orc1 in complex with the nucleosome core particle, revealing that Orc1 interacts with the histone H4 tail irrespective of K16 acetylation; a modification that regulates accessibility to chromatin.

    • Pablo De Ioannes
    • Victor A. Leon
    • Karim-Jean Armache
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11

  • The cryo-EM structure of DNA-assembled histone pairs Hβ-Hα and Hδ-Hγ from Marseillevirus, a nucleocytoplasmic large DNA virus, reveals that these proteins form viral nucleosomes with highly conserved features when compared to canonical eukaryotic nucleosomes.

    • Marco Igor Valencia-Sánchez
    • Stephen Abini-Agbomson
    • Karim-Jean Armache
    Research
    Nature Structural & Molecular Biology
    Volume: 28, P: 413-417