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Showing 1–7 of 7 results
Advanced filters: Author: Pamela Ferretti Clear advanced filters
  • Here, with metagenomic analyses on longitudinal samples collected from 195 mother-infant pairs, the authors show that the breast milk microbiome contributes to infant gut assembly through bacterial strain sharing and antimicrobial resistance gene overlap during the first six months of life.

    • Pamela Ferretti
    • Mattea Allert
    • Ran Blekhman
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15
  • In this Review, Ferretti et al. discuss advances in our understanding of interactions between the human genome and the microbiome, including the effects of the microbiome on host gene regulation.

    • Pamela Ferretti
    • Kelsey Johnson
    • Ran Blekhman
    Reviews
    Nature Reviews Genetics
    Volume: 27, P: 62-80
  • A survey of species-level genes from 13,174 publicly available metagenomes shows that most species-level genes are specific to a single habitat, encode a small number of protein families and are under low positive (adaptive) pressure.

    • Luis Pedro Coelho
    • Renato Alves
    • Peer Bork
    Research
    Nature
    Volume: 601, P: 252-256
  • A consortium reports the tripling of the number of genetic markers in Phase II of the International HapMap Project. This map of human genetic variation will continue to revolutionize discovery of susceptibility loci in common genetic diseases, and study of genes under selection in humans.

    • Kelly A. Frazer (Principal Investigator)
    • Dennis G. Ballinger
    • John Stewart
    Research
    Nature
    Volume: 449, P: 851-861
  • Large-scale metagenomic analyses are vastly increasing the rate of discovery of variation within species but they are also leading to scientific and semantic challenges. Bork and colleagues highlight the advances and challenges that are resulting from the use of metagenomic data to study within-species diversity.

    • Thea Van Rossum
    • Pamela Ferretti
    • Peer Bork
    Reviews
    Nature Reviews Microbiology
    Volume: 18, P: 491-506
  • Sabeti et al. build on their This paper builds on previous work of detecting selection on human genes, using the many more markers available in the Phase II HapMap project. Three examples of apparent population-specific selection based on geographic area are described, and how these may relate to human biology is discussed.

    • Pardis C. Sabeti
    • Patrick Varilly
    • John Stewart
    Research
    Nature
    Volume: 449, P: 913-918