The transcription factor Ets2 is expressed in the extraembryonic ectoderm tropoblast during gastrulation. Here, the authors use Ets2 knock-out mice to show that Ets2 signalling is required for gastrulation, primitive streak elongation and development and the mesoderm epithelial-to-mesenchymal transition.
- Christiana Polydorou
- Pantelis Georgiades
