Rab-controlled trafficking pathways have been implicated in tumourigenesis. Here the authors show that Rab37 suppresses metastasis by regulating the exocytosis of tissue inhibitor of metalloproteinase 1 to repress matrix metalloproteinase 9 and represents a novel prognostic marker for lung cancer.
- Chung-Han Tsai
- Hung-Chi Cheng
- Yi-Ching Wang
