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Showing 1–3 of 3 results
Advanced filters: Author: Param Priya Singh Clear advanced filters

  • Characterizing molecular aging features is crucial for understanding systemic and local factors contributing to the aging process. Here Costa, Chen et al. performed RNA sequencing on 13 tissues across six ages in male and female African turquoise killifish. This sex-balanced killifish aging atlas provides a comprehensive resource for studying aging dynamics across tissues in the killifish—a powerful, short-lived vertebrate model of aging.

    • Emma K. Costa
    • Jingxun Chen
    • Tony Wyss-Coray
    ResearchOpen Access
    Nature Aging
    Volume: 6, P: 636-664

  • High-throughput analysis of cellular landscapes is an important tool to decipher the molecular mechanisms driving aging and disease. Here, Singh and Benayoun discuss key considerations in the design and analysis of omic data to gain robust and reproducible insights into the aging process.

    • Param Priya Singh
    • Bérénice A. Benayoun
    Reviews
    Nature Aging
    Volume: 3, P: 921-930

  • Recent studies suggest that progranulin has an important role in lysosome biogenesis and innate immunity in the brain. In this Progress article, Kao and colleagues suggest that progranulin also plays a part in suppressing excessive neuroinflammation during ageing.

    • Aimee W. Kao
    • Andrew McKay
    • Eric J. Huang
    Reviews
    Nature Reviews Neuroscience
    Volume: 18, P: 325-333