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Showing 1–4 of 4 results
Advanced filters: Author: Parinaz Fozouni Clear advanced filters

  • Viruses can insert a copy of their genetic sequence into a host cell’s genome. If the insertion fails, gene expression of unintegrated viral DNA in the nucleus is silenced. How this process occurs has now been uncovered.

    • Parinaz Fozouni
    • Melanie Ott
    News & Views
    Nature
    Volume: 564, P: 193-194

  • Deploying two unrelated CRISPR nucleases in tandem, with multiplexed CRISPR RNAs and a chemically stabilized activator, creates a simple, one-step assay that can rapidly detect attomolar concentrations of RNA without needing target amplification.

    • Tina Y. Liu
    • Gavin J. Knott
    • Jennifer A. Doudna
    Research
    Nature Chemical Biology
    Volume: 17, P: 982-988

  • Xu et al. report that nuclear SIRT1 is recognized as an autophagy substrate during senescence and also observe ageing of the immune system.

    • Caiyue Xu
    • Lu Wang
    • Shelley L. Berger
    Research
    Nature Cell Biology
    Volume: 22, P: 1170-1179