DNA replication requires re-establishment of chromatin structure, which involves incorporation of newly synthesized histones. Here, Klimovskaia et al.show that phosphorylation of the histone chaperone Asf1 by Tousled-Like Kinase stimulates its ability to bind histones, thus promoting chromatin assembly.
- Ilnaz M. Klimovskaia
- Clifford Young
- Anja Groth
