Mauerhofer et al. examine 80 species of methanogenic archaea at high pressures and evaluate growth and methane production, identifying Methanotorris igneus and Methanocaldococcoccus jannaschii as high-pressure methane cell factories. They find that high-performance methanogens are covered with an S-layer and harbour the amino acid motif Tyrα444 Glyα445 Tyrα446 in the alpha subunit of the methyl-coenzyme M reductase.
- Lisa-Maria Mauerhofer
- Sara Zwirtmayr
- Simon K.-M. R. Rittmann