The small GTPases Rnd2 and Rnd3 act downstream of proneural factors to control the migrating behaviour of neurons in the mouse embryonic cerebral cortex. Here, Azzarelli et al. show that Rnd3 binding to the semaphorin receptor PlexinB2 fine-tunes the levels of active RhoA required for cortical neuron migration.
- Roberta Azzarelli
- Emilie Pacary
- François Guillemot
