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Showing 1–4 of 4 results
Advanced filters: Author: Patrick Metang Clear advanced filters
  • The relative contribution of lipid catabolism on fasting-induced longevity was unknown. Authors showed lifespan extension from fasting depend on silencing lipid catabolism upon nutrient replenishment through phosphorylation of NHR-49 by KIN-19.

    • Lexus Tatge
    • Juhee Kim
    • Peter M. Douglas
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-22
  • Neurons deploy diverse adaptive strategies to ensure survival and neurotransmission amid cellular stress. Here authors show that stressed dopaminergic neurons actively induce a state of transmissive dormancy and appear to prioritize viability over functionality.

    • Kielen R. Zuurbier
    • Rene Solano Fonseca
    • Peter M. Douglas
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19
  • The effects of vaccines on human dendritic cells (DCs) are incompletely understood. Here the authors build a transcriptional modular network based on in vitroinfection of human DCs and apply it for the characterization of the DC response to 13 different vaccines.

    • Romain Banchereau
    • Nicole Baldwin
    • Virginia Pascual
    ResearchOpen Access
    Nature Communications
    Volume: 5, P: 1-14